85 million major scientific research project funds approved to boost the precision of medical instrument development

Recently, led by the Harbin Medical University, the National Natural Science Fund Project “major scientific instruments and radionuclide synchronous integrated tumor molecular imaging instrument” (project number: 81627901) officially approved, Professor Shen Baozhong served as chief scientist.

The National Natural Science Foundation of major scientific research project is the instrument foundation so far the largest amount of funding the project (85 million yuan).

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The project is the first time the doctor served as chief scientist of the organization and implementation of Harbin Medical University, Peking University, Shanghai Jiao Tong University, Chinese Academy of Sciences led the Wuhan number, Shenzhen Institute of Advanced Institute, Shandong Academy of Medical Sciences, Huazhong University of Science and Technology and other 7 domestic research institutes jointly, joint research, the key technology to solve the problems in the diagnosis and treatment of early cancer. The implementation of the project in the project, in the process, the China Academy of Engineering Yang Baofeng’s encouragement and support.

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The molecular events driving and control the occurrence and development of tumor, its mechanism is not clear it is a bottleneck problem for cancer research, which leads to poor treatment effect (tumor in China average 5 years survival rate is only 31%, less than 10% of lung cancer). Therefore, how to reveal the molecular events in vivo, has become a major scientific proposition, but also the next generation imaging equipment development direction, related technology research and development we are in a critical period of strategic opportunities.

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The instrument is based on the principle of magnetic resonance, for the first time in the world of multi-core synchronous integrated magnetic resonance imaging in vivo, both through the key technology of multi component integration research and development of New Nuclide nuclide synchronous excitation and acquisition, control and imaging system and image, multi nuclides in the tumor of the key molecular targets, image to reveal the tumor metabolism, ion homeostasis and growth of micro environment information.

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Its significance lies in:

(1) radionuclide imaging is the gene and protein of tumor molecular events “because” the image, instead of the tumor grows to a certain size, form “fruit” imaging, it will completely change the traditional medical imaging technology and mode of thinking mode, has great significance in early diagnosis of tumor;

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(2) due to the synchronous reveals the key molecular events in the occurrence and development of tumor and mechanism in vivo, which will study on the mechanism of tumor have a tremendous role;

(3) as imaging gene and molecular level, will change the future of tumor diagnosis and treatment mode, become the important technical support of precision medicine, and has great application potential in transformation.

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Because there is great theoretical innovation and breakthroughs in key technologies, instrument design ideas and implementation schemes of the National Natural Science Fund Committee, the national Ministry of science and technology experts (including more than 20 academicians) are highly appraised; at the same time, China medical imaging equipment development and production of leading enterprises: Shanghai movie (medical group chairman Xi Jinping repeatedly visited) quickly follow professional, technical team to send the strongest strength to actively participate in the implementation of the project, and will focus on the project as the company cooperation, hope this project as an opportunity for transformation, become the leading imaging equipment of the next generation technology.

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